Anti-PD-1 Monoclonal Antibody MEDI0680
Information
- Drug Name
- Anti-PD-1 Monoclonal Antibody MEDI0680
- Description
- Entry(CIViC)
- 2
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| transitional cell carcinoma |
MSH2 LOSS ( ENST00000233146.7 ) MSH2 LOSS ( ENST00000233146.7 ) |
C |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 26674132 | Detail |
| transitional cell carcinoma |
MSH6 LOSS ( ENST00000234420.11 ) MSH6 LOSS ( ENST00000234420.11 ) |
C |
Predictive
|
Supports
|
Sensitivity/Response | 3 | 26674132 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| Case report of a 45-year old woman of Japanese des... | MSH2 |
MSH2 LOSS ( ENST00000233146.7 ) MSH2 LOSS ( ENST00000233146.7 ) |
Sensitivity | true | CIViC Evidence | detail |
| Case report of a 45-year old woman of Japanese des... | MSH6 |
MSH6 LOSS ( ENST00000234420.11 ) MSH6 LOSS ( ENST00000234420.11 ) |
Sensitivity | true | CIViC Evidence | detail |